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2022

Cao, X. et al.: A comparative study of persistent DNA oxidation and chromosomal instability induced in vitro by oxidizers and reference airborne particles. Mutat. Res. Genet. Toxicol. Environ. Mutagen. 874-875, 503446. DOI: 10.1016/j.mrgentox.2022.503446 (2022)

Hartner, E.; Paul, A.; Käfer, U.; Czech, H.; Hohaus, T.; Gröger, T.; Sklorz, M.; Jakobi, G.; Orasche, J.; Jeong, S.; Brejcha, R.; Ziehm, T.; Zhang, Z.-H.; Schnelle-Kreis, J.; Adam, T.; Rudich, Y.; Kiendler-Scharr, A.; Zimmermann, R. On the Complementarity and Informative Value of Different Electron Ionization Mass Spectrometric Techniques for the Chemical Analysis of Secondary Organic Aerosols. ACS Earth Space Chem. 6 (5), 1358–1374. DOI: 10.1021/acsearthspacechem.2c00039 (2021)

Ihantola, T. et al.: Genotoxic and inflammatory effects of spruce and brown coal briquettes combustion aerosols on lung cells at the air-liquid interface. Sci. Tot. Environ. 806 (Pt 1), 150489. DOI: 10.1016/j.scitotenv.2021.150489 (2022)

Li, C.; Fang, Z.; Czech, H.; Schneider, E.; Rüger, C. P.; Pardo, M.; Zimmermann, R.; Chen, J.; Laskin, A.; Rudich, Y. pH modifies the oxidative potential and peroxide content of biomass burning HULIS under dark aging. Sci. Tot. Environ. 2022, 834, 155365. DOI: 10.1016/j.scitotenv.2022.155365 (2022)

Offer, S. et al.: Effect of Atmospheric Aging on Soot Particle Toxicity in Lung Cell Models at the Air-Liquid Interface: Differential Toxicological Impacts of Biogenic and Anthropogenic Secondary Organic Aerosols (SOAs). Environ. Health Perspect. 130 (2), 27003. DOI: 10.1289/EHP9413 (2022)

Pardo, M.; Offer, S.; Hartner, E.; Di Bucchianico, S.; Bisig, C.; Bauer, S.; Pantzke, J.; Zimmermann, E. J.; Cao, X.; Binder, S.; Kuhn, E.; Huber, A.; Jeong, S.; Käfer, U.; Schneider, E.; Mesceriakovas, A.; Bendl, J.; Brejcha, R.; Buchholz, A.; Gat, D.; Hohaus, T.; Rastak, N.; Karg, E.; Jakobi, G.; Kalberer, M.; Kanashova, T.; Hu, Y.; Ogris, C.; Marsico, A.; Theis, F.; Shalit, T.; Gröger, T.; Rüger, C. P.; Oeder, S.; Orasche, J.; Paul, A.; Ziehm, T.; Zhang, Z.-H.; Adam, T.; Sippula, O.; Sklorz, M.; Schnelle-Kreis, J.; Czech, H.; Kiendler-Scharr, A.; Zimmermann, R.; Rudich, Y. Exposure to naphthalene and β-pinene-derived secondary organic aerosol induced divergent changes in transcript levels of BEAS-2B cells. Environ. Int. 166, 107366. DOI: 10.1016/j.envint.2022.107366 (2022)

Passig, J. et al.: Single-particle characterization of polycyclic aromatic hydrocarbons in background air in northern Europe. Atmos. Chem. Phys. 22 (2), 1495–1514. DOI: 10.5194/acp-22-1495-2022 (2022)

Schneider, E.; Czech, H.; Popovicheva, O.; Lütdke, H.; Schnelle-Kreis, J.; Khodzher, T.; Rüger, C. P.; Zimmermann, R. Molecular Characterization of Water-Soluble Aerosol Particle Extracts by Ultrahigh-Resolution Mass Spectrometry: Observation of Industrial Emissions and an Atmospherically Aged Wildfire Plume at Lake Baikal. ACS Earth Space Chem. 6 (4), 1095–1107. DOI: 10.1021/acsearthspacechem.2c00017 (2022)

Zhang, Z.-H. et al.: Are reactive oxygen species (ROS) a suitable metric to predict toxicity of carbonaceous aerosol particles? Atmos. Chem. Phys. 22 (3), 1793–1809. DOI: 10.5194/acp-22-1793-2022 (2022)

2021

Binder, S. et al.: In vitro genotoxicity of dibutyl phthalate on A549 lung cells at air-liquid interface in exposure concentrations relevant at workplaces. Environ. Mol. Mutagen. 62 (9), 490–501. DOI: 10.1002/em.22464 (2021)

Cao, X. et al.: Adenine derivatization for LC-MS/MS epigenetic DNA modifications studies on monocytic THP-1 cells exposed to reference particulate matter. Anal. Biochem. doi.org/10.1016/j.ab.2021.114127 (2021)

Dean, J. et al.: Above us only sky. Commun. Earth Environ. 2 (1). DOI: 10.1038/s43247-021-00245-0 (2021)

Fang, Z. et al.: Secondary organic aerosols produced from photochemical oxidation of secondarily evaporated biomass burning organic gases: Chemical composition, toxicity, optical properties, and climate effect. Environ. Int. 157, 106801. DOI: 10.1016/j.envint.2021.106801 (2021)

Gat, D. et al.: Size-Resolved Community Structure of Bacteria and Fungi Transported by Dust in the Middle East. Front. Microbiol. 12. DOI: 10.3389/fmicb.2021.744117 (2021)

Gehm, C. et al.: Hyper-fast gas chromatography and single-photon ionisation time-of-flight mass spectrometry with integrated electrical modulator-based sampling for headspace and online VOC analyses. Analyst 146, 3137-3149 (2021)

Gupta, S. S. et al.: An integrative workflow to prioritize toxicity initiation events from air-liquid-interface exposure of human lung cells to combustion aerosols: First application to emissions from a heavy fuel oil or diesel fuel operated ship engine. Research Square (preprint, DOI: 10.21203/rs.3.rs-152521/v1) (2021)

Kösling, P. et al.: Vacuum Laser Photoionization inside the C-trap of an Orbitrap Mass Spectrometer: Resonance-Enhanced Multiphoton Ionization High-Resolution Mass Spectrometry. Anal. Chem. 93 (27), 9418–9427. DOI: 10.1021/acs.analchem.1c01018 (2021)

Li, C., et al.: Correcting micro-aethalometer absorption measurements for brown carbon aerosol. Sci. Tot. Environ. 777, 146143 (2021)

Martens, P. et al.: Emissions of Gases and Volatile Organic Compounds from Residential Heating: A Comparison of Brown Coal Briquettes and Logwood Combustion. Energy Fuels 35 (17), 14010–14022. DOI: 10.1021/acs.energyfuels.1c01667 (2021)

Momenimovahed, A. et al.: Comparison of black carbon (BC) measurement techniques for marine engine emissions using three marine fuel types. Aerosol Science Technology 55, 46-62, doi.org/10.1080/02786826.2021.1967281 (2021)

Nguyen, D. L. et al. Carbonaceous aerosol composition in air masses influenced by large-scale biomass burning: a case study in Northwestern Vietnam. Atmos. Chem. Phys. 21, 8293–8312, 2021(2021)

Ogris, C., et al.: Versatile knowledge guided network inference method for prioritizing key regulatory factors in multi-omics data. Scientific reports 11, 6806 (2021)

Pardo, M. et al.: Toxicity of Water- and Organic-Soluble Wood Tar Fractions from Biomass Burning in Lung Epithelial Cells. Chemical Research in Toxicology, https://doi.org/10.1021/acs.chemrestox.1c00020 (2021)

Passig, J., et al.: Detection of ship plumes from residualfuel operation in emission control areas using single-particle mass spectrometry. Atmos. Meas. Tech., 14, 4171–4185 (2021)

Peng, X.; Gat, D.; Paytan, A.; Rudich, Y. The Response of Airborne Mycobiome to Dust Storms in the Eastern Mediterranean. J. Fungi 7 (10). DOI: 10.3390/jof7100802 (2021)

Rudich, J., et al.: The Biogeography of Dust in the Eastern Mediterranean. Research Square (preprint, DOI:10.21203/rs.3.rs-149876/v1) (2021)

Rüger, C. P.; Le Maître, J.; Riches, E.; Palmer, M.; Orasche, J.; Sippula, O.; Jokiniemi, J.; Afonso, C.; Giusti, P.; Zimmermann, R. Cyclic Ion Mobility Spectrometry Coupled to High-Resolution Time-of-Flight Mass Spectrometry Equipped with Atmospheric Solid Analysis Probe for the Molecular Characterization of Combustion Particulate Matter. J. Am. Soc. Mass Spectrom. 32 (1), 206–217. DOI: 10.1021/jasms.0c00274 (2021)

2020

Hartikainen, A. et al.: Photochemical transformation of residential wood combustion emissions: Dependence of organic aerosol composition on OH exposure. Atmos. Chem. Phys. 20, 6357-6378 (2020)

Ihantola, T. et al.: Influence of wood species on toxicity of log-wood stove combustion aerosols: A parallel animal and air-liquid interface cell exposure study on spruce and pine smoke. Part. Fibre Toxicol. 17:27 (2020)

Li, C. et al.: Formation of Secondary Brown Carbon in Biomass Burning Aerosol Proxies through NO₃ Radical Reactions. Environ. Sci. Technol. 54, 1395-1405 (2020)

Li, C. et al.: Laboratory Insights into the Diel Cycle of Optical and Chemical Transformations of Biomass Burning Brown Carbon Aerosols. Environ. Sci. Technol. 54 (19), 11827–11837. DOI: 10.1021/acs.est.0c04310 (2020)

Pardo, M. et al.: Particulate matter toxicity is Nrf2 and mitochondria dependent: The roles of metals and polycyclic aromatic hydrocarbons. Chem. Res. Toxicol. 33, 5, 1110–1120 (2020)

Pardo, M., et al.: Mechanisms of lung toxicity induced by biomass burning aerosols. Part. Fibre Toxicol. 17, 4 (2020)

Passig, J. et al.: Resonance-enhanced detection of metals in aerosols using single-particle mass spectrometry. Atmos. Chem. Phys. 20, 7139-7152 (2020)

Rüger, C. P.: Cyclic ion mobility spectrometry coupled to high-resolution time-of-flight mass spectrometry equipped with atmospheric solid analysis probe for the molecular characterization of combustion particulate matter. J. Am. Soc. Mass. Spectr., DOI 10.1021/jasms.0c00274 (2020)

 

2019

Chowdhury, P. H., et al.: Connecting the Oxidative Potential of Secondary Organic Aerosols with Reactive Oxygen Species in Exposed Lung Cells. Environ. Sci. Technol. 53, 23, 13949–13958 (2019)

Ihalainen, M. et al.: A novel high-volume Photochemical Emission Aging flow tube Reactor (PEAR). Aerosol Sci. Technol. 53, 276-294 (2019)

Jiang, X., et al.: Hydrophobic Organic Components of Ambient Fine Particulate Matter (PM2.5) Associated with Inflammatory Cellular Response. Environ. Sci. Technol. 53, 17, 10479–10486 (2019)

Li, C. et al.: Dynamic changes in optical and chemical properties of tar ball aerosols by atmospheric photochemical aging. Atmos. Chem. Phys. 19, 139-163 (2019)

Miersch, T. et al.: Impact of photochemical ageing on Polycyclic Aromatic Hydrocarbons (PAH) and oxygenated PAH (Oxy-PAH/OH-PAH) in logwood stove emissions. Sci. Total Environ. 686, 382-392 (2019)

Schade, J. et al.: Spatially shaped laser pulses for the simultaneous detection of polycyclic aromatic hydrocarbons as well as positive and negative inorganic ions in single particle mass spectrometry. Anal. Chem. 91, 10282-10288 (2019)

 

Wissenschaftliche Vorarbeiten für aeroHEALTH-relevante Ziele sind in folgenden Publikationen beschrieben.

 

Czech, H. et al.
Chemical composition and speciation of particulate organic matter from modern residential small-scale wood combustion appliances.
Science of the Total Environment, 612, 636-648 (2018)

Pardo, M. et al.
Seasonal variations in fine particle composition from Beijing prompt oxidative stress response in mouse lung and liver.
Science of the Total Environment, 12;626, 147-155 (2018)

Wolf, F. et al.
SCANPY: Large-scale single-cell gene expression data analysis.
Genome Biol. 19:15 (2018)

Aichler, M. et al.
N-acyl Taurines and Acylcarnitines cause an Imbalance in Insulin Synthesis and Secretion Provoking β Cell Dysfunction in Type 2 Diabetes.
Cell Metab. Elsevier 25(6):1334–47 (2017)

Pardo, M. et al.
Mitochondria-mediated oxidative stress induced by desert dust in rat alveolar macrophages.
AGU GEOhealth, 1: 4-16 (2017)

Passig, J. et al.
Aerosol mass spectrometer for simultaneous detection of polyaromatic hydrocarbons and inorganic components from individual particles.
Analytical Chemistry 89, 6341-6345 (2017)

Hohaus, T. et al.
A new plant chamber facility, PLUS, coupled to the atmospheric simulation chamber SAPHIR.
Atmos. Meas. Tech., 9, 1247 – 1259, 2016

Kiendler-Scharr, A. et al.
Ubiquity of organic nitrates from nighttime chemistry in the European submicron aerosol.
Geophys. Res. Lett., 43, 7735–7744, (2016)